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  • Research
    • Current Research
    • What is Progeria?
    • Publications
  • Contact
  • Meet The Team

A tissue engineered blood vessel model of Hutchinson-Gilford Progeria syndrome using Human iPSC-derived smooth muscle cells

  • Post author:caolab75@gmail.com
  • Post published:August 15, 2017
  • Post category:Articles

Continue ReadingA tissue engineered blood vessel model of Hutchinson-Gilford Progeria syndrome using Human iPSC-derived smooth muscle cells

Lamin A and microtubules collaborate to maintain nuclear morphology

  • Post author:caolab75@gmail.com
  • Post published:May 30, 2017
  • Post category:Articles

Continue ReadingLamin A and microtubules collaborate to maintain nuclear morphology

Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

  • Post author:caolab75@gmail.com
  • Post published:May 30, 2017
  • Post category:Articles

Continue ReadingAnti-Aging Potentials of Methylene Blue for Human Skin Longevity

Lamin A and microtubules collaborate to maintain nuclear morphology

  • Post author:caolab75@gmail.com
  • Post published:April 12, 2017
  • Post category:Articles

Continue ReadingLamin A and microtubules collaborate to maintain nuclear morphology

Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

  • Post author:caolab75@gmail.com
  • Post published:December 8, 2016
  • Post category:Articles

Continue ReadingComparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome

  • Post author:caolab75@gmail.com
  • Post published:December 1, 2016
  • Post category:Articles

Continue ReadingLoss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome

Mechanisms of genome instability in Hutchinson-Gilford progeria

  • Post author:caolab75@gmail.com
  • Post published:November 10, 2016
  • Post category:Articles

Continue ReadingMechanisms of genome instability in Hutchinson-Gilford progeria

Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria

  • Post author:caolab75@gmail.com
  • Post published:November 5, 2015
  • Post category:Articles

Continue ReadingMethylene blue alleviates nuclear and mitochondrial abnormalities in progeria

Phenotype-Dependent Coexpression Gene Clusters: Application to Normal and Premature Ageing

  • Post author:caolab75@gmail.com
  • Post published:January 2, 2015
  • Post category:Articles
  • Post comments:0 Comments

Continue ReadingPhenotype-Dependent Coexpression Gene Clusters: Application to Normal and Premature Ageing

Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1

  • Post author:caolab75@gmail.com
  • Post published:April 10, 2014
  • Post category:Articles

Continue ReadingMechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1
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Cao Lab

My laboratory would like to further examine the causative relationship between progerin production and the aging process, to study the regulation of progerin production in normal cells, and to determine the contribution of progerin in normal human aging.

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